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Inside Noni: The Top 4 Most Beneficial Compounds

By: Steve Frailey Thursday February 18, 2016 comments Tags: natural antioxidants, scopoletin, noni for pain, natural pain relief, noni health benefits, organic pain relief

In today’s world of highly-processed, nutritionless foods, it’s hard to be sure you’re getting access to the countless micronutrients available from the wide variety foods available to us. Americans in particular are eating more and more calories, while obtaining fewer and fewer nutrients.

Eating a diet of mainly whole, raw foods helps, but even our fruits and vegetables have depleted nutrients due to lost soil fertility, poor agricultural practices, and selective breeding for shelf life rather than nutrition. Organic is better, but even industrially-produced organic foods may be nutritionally lacking.

Luckily, nature provides foods like noni, which act as a broad-based raw food supplement which provides  natural antioxidant protection against free radical damage, boosts the immune system and supports a healthy response to inflammation

The whole noni fruit is so potent because it’s packed with over 165 beneficial compounds, including vitamins, minerals, 17 out of 20 essential amino acids, countless beneficial enzymes, and many others. Here are four of the compounds in noni that have the biggest impact on health, including a few you may not have heard of!

1. Scopoletin

This compound is a phytochemical, which means it’s a biologically active compound in a plant. Scopoletin is found in the roots of plants of the genus Scopolia, including chicory and stinging nettle. But it’s also found in the pulp of raw noni fruit!

Powerful Pain Reliever

In many studies, scopoletin has made a name for itself as a potent pain reliever. One study published in Phytotherapy Research (24[1]:38-42) by researchers from the University Clinic in Hamburg, Germany, reported that noni fruit’s analgesic activity “reduced the pain sensitivity comparably to the central analgesic drug tramadol.” When extracts of noni fruit puree were applied, the “effect was comparable to hydrocortisone.” The best part — noni fruit has no side effects or known toxic level.

The compound responsible was believed to be scopoletin. Scopoletin is a powerful anti-inflammatory, which may contribute to this ability. Basically, scopoletin is your best friend when recovering from injury. 

Mood Enhancer

Scopoletin’s pain relieving power may be related to another known effect of the phytochemical: mood elevation. This compound binds with serotonin to keep levels elevated. Serotonin is a neurotransmitter that regulates mood, sleep, hunger, temperature, and more.

For this reason, scopoletin is being tested as a possible depression treatment. It’s mood-enhancing properties combined with its pain relieving properties make Noni a possible quality of life enhancement for people undergoing chemotherapy & radiation treatment.

2. Anthraquinones

Noni also contains a wide variety of anthraquinones. Anthraquinones are a type of phenol produced by some plants. Many phenols, including a number of anthraquinones, have shown evidence of being beneficial for human health.

Some of the anthraquinones in noni fight enzymes that break down collagen in the body, which may slow down the aging process. Many anthraquinones also help regulate smooth digestion.


The anthraquinone most of interest to noni researchers is called damnacanthal, which likely helps protect plants from UV damage and parasites.

Damnacanthal has been shown to stimulate T cell activity which may help address various forms of damaged cells. Go to and look up “damnacanthal noni” if you want to learn the specifics.

There is also evidence that damnacanthal deters parasites!

Dietary Fiber: Soluble & Insoluble

Fiber, of both the soluble and insoluble varieties, is critical for good health. Noni has both in abundance, but only if you preserve the raw pulp. Noni juice contains very little fiber, whereas Noni Fruit Leather is a very rich source.

Soluble fiber turns into a gel during digestion by absorbing water. This process slows digestion, ensuring maximal nutritional absorption and good elimination. But soluble fiber is also crucial for regulating weight and blood sugar levels.

Insoluble fiber doesn’t absorb water or break down much during digestion. It remains more or less intact, and this is what makes it so valuable for colon health. It’s especially good at reducing risk of hemmorhoids.

But the fact is, you need both soluble and insoluble fiber for optimum health. Luckily, noni fruit, including Noni Fruit Leather is a great source of both kinds of dietary fiber. But don’t go for the noni juice — that’s missing the pulp with all the good stuff!

Vitamin C

We all know that we need more antioxidants in our diet, and we all want to age more gracefully, so vitamin C should be a natural choice. Noni Fruit Leather is a great source of Vitamin C, along with many other natural antioxidants.

Generally, antioxidants prevent the harmful effects of oxidizing agents. They hinder the breakdown through oxidization of substances in the body, especially fats. When substances in our body oxidize, they can accelerate the aging process or even increase risk of cancer.

Vitamin C, as a powerful antioxidant, hunts down and neutralizes free radicals. It’s also closely associated with the production of collagen. If we want to slow the aging process, it’s essential for our bodies to continue producing collagen and slow collagen breakdown as much as possible.

Collagen is found in the skin, blood vessels, teeth, bone, tendons, and connective tissue. If collagen breaks down, wrinkles start to form. If collagen production is renewed, those lines can fade, dropping years from your face.

When we consume vitamin C, the cross-connections between amino acids (the building blocks of proteins like collagen) increase and strengthen. This increased cross-connection makes the structural tissues more resilient against further destruction by free radicals and age.

Has Noni Fruit Leather improved your health? Tell us your story in the comments! We love hearing how noni changes lives.


Steve Frailey

About the Author: Steve Frailey

My wife and I (Steve Frailey) moved to Kauai, Hawaii in 1982 from our organic farm in California. There were no roads, electricity, water or buildings but lots of Noni trees (Morinda Citrifolia) in our valley. We also developed a deep relationship with Noni that was growing all through our valley.  Today we run our Hawaiian Organic Noni farm, and share the gift of health with people throughout the world.